Changing Shape of Coronavirus: The researchers found that the spike protein in SARS-CoV-19 after attached to a human cell, wrapped itself inside it, and changed its shape after the formation of a strong hairpin.
It is the corona or corona-like protein that comes from the body of the coronavirus, hence its called ‘coronavirus’.
In SARS-CoV-2 coronavirus, it is a protein spike that initiates the infection process in the human cell. It attaches to a human enzyme called an ACE2 receptor, before entering the cell and making many copies of it. Studies show an unexpected change in the hairpin state after protein synthesis with the ACE2 receptor. In fact, the researchers found that the formation of the “back” was manifested before assembly – without the binding virus in the cell. Examining different structures can help prevent SARS-CoV-2 from exploding. Studies show that the virus is active in different parts of the world at different times.
The post-fusion structure promotes antibodies that do not reduce the virus. In fact, these types of antibodies act as tricks to damage the immune system. Antibodies that specifically target the post-fusion state cannot prevent membrane aggregation (infiltration) because it is too late. The sugar molecules in both the “front” and “rear” strains are called glycans, which have equal space on their faces. Glycans are another factor in preventing virus detection. The researchers believe that these results contributed to the development of the policy.
Many vaccines are currently under development which uses spike protein to boost immunity.
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